Valbenazine – 25 mg

Brand:
Cayman
CAS:
1025504-45-3
Storage:
-20
UN-No:
Non-Hazardous - /

Valbenazine is an inhibitor of vesicular monoamine transporter 2 (VMAT2; Kis = 110 and 150 nM in rat striatum homogenates and human platelets, respectively).{47247} It is selective for VMAT2 over a panel of 80 receptors, transporters, and ion channels, including the serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, and 5-HT2B and dopamine D1 and D2 receptors. Valbenazine induces ptosis in rats, indicating norepinephrine depletion. Formulations containing valbenazine have been used in the treatment of tardive dyskinesia.  

 

Available on backorder

SKU: 26809 - 25 mg Category:

Description

An inhibitor of VMAT2 (Kis = 110 and 150 nM in rat striatum homogenates and human platelets, respectively); selective for VMAT2 over a panel of 80 receptors, transporters, and ion channels; increases ptosis in rats


Formal name: L-valine, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester

Synonyms:  NBI-98854

Molecular weight: 418.6

CAS: 1025504-45-3

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Neuroscience|Behavioral Neuroscience