A broad-spectrum

Umifenovir (hydrochloride) – 10 mg

Brand:
Cayman
CAS:
131707-23-8
Storage:
-20
UN-No:
Non-Hazardous - /

Umifenovir is a broad-spectrum, indole-based antiviral compound that blocks viral fusion with target membranes, prohibiting viral entry into cells. Because umifenovir targets a common critical step for viral replication, it is effective against numerous viruses, including influenza A, B, and C and hepatitis B and C (IC50s range from 3-12.5 µg/ml).{27500} Besides its antiviral action, umifenovir has been reported to produce an immunomodulatory response by inducing interferon production and stimulating the phagocytic function of macrophages.{27500}  

 

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Description

A broad-spectrum, indole-based antiviral compound that blocks viral fusion with target membranes, prohibiting viral entry into cells; effective against numerous viruses, including influenza A, B, and C and hepatitis B and C (IC50s range from 3-12.5 µg/ml)

Formal name: 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic acid, ethyl ester, monohydrochloride

Synonyms: 

Molecular weight: 513.9

CAS: 131707-23-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals|Entry/fusion Inhibitors||Research Area|Immunology & Inflammation|Pulmonary Diseases|COVID-19||Research Area|Infectious Disease|Viral Diseases|Coronaviruses||Research Area|Infectious Disease|Viral Diseases|Hepatitis||Research Area|Infectious Disease|Viral Diseases|Influenza||Research Area|Infectious Disease|Viral Diseases|Zika

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