An endogenous nucleotide sugar that binds the P2Y14 receptor (EC50 = 0.35 μM) as well as GPR17; induces oligodendrocyte differentiation at a maximal concentration of 100 μM

UDP-α-D-Glucose (sodium salt) – 1 g

Brand:
Cayman
CAS:
28053-08-9
Storage:
-20
UN-No:
Non-Hazardous - /

UDP-α-D-Glucose is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It has been shown to bind the P2Y14 receptor (EC50 = 0.35 μM), an atypical P2Y receptor involved in the activation of dendritic cells and glial cells.{23976} It can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM.{16468}  

 

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Description

An endogenous nucleotide sugar that binds the P2Y14 receptor (EC50 = 0.35 μM) as well as GPR17; induces oligodendrocyte differentiation at a maximal concentration of 100 μM

Formal name: uridine 5’-(trihydrogen diphosphate), P’-α-D-glucopyranosyl ester, disodium salt

Synonyms:  UDPG|UDP-Glucose|Uridine-5′-diphosphoglucose

Molecular weight: 610.3

CAS: 28053-08-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism

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