A potent inhibitor of DPP-2 (IC50 = 0.48 nM); inhibits DPP-4 (IC50 = 165 mM)

UAMC 0039 (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
697797-51-6
Storage:
-20
UN-No:
Non-Hazardous - /

UAMC 0039 is a potent inhibitor of dipeptidyl peptidase 2 (DPP-2; IC50 = 0.48 nM).{34797} It also inhibits DPP-4 (IC50 = 165 µM). DPP-2 is thought to be involved in degradation of collagen, substance P, and some proline-containing neuropeptides.{34797,34798,34799}  

 

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Description

A potent inhibitor of DPP-2 (IC50 = 0.48 nM); inhibits DPP-4 (IC50 = 165 mM)

Formal name: (2S)-2-amino-4-[[(4-chlorophenyl)methyl]amino]-1-(1-piperidinyl)-1-butanone, dihydrochloride

Synonyms: 

Molecular weight: 382.8

CAS: 697797-51-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Cell Biology|Proteolysis|Lysosomal Proteases||Research Area|Neuroscience|Neuroendocrinology

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