A phenol with diverse biological activities; fungicidal against H. capsulatum and C. posadasii (MFCs = 170-710 and 1

Tyrosol – 500 g

Brand:
Cayman
CAS:
501-94-0
Storage:
-20
UN-No:
Non-Hazardous - /

Tyrosol is a phenol that has been found in olives and olive oil and has diverse biological activities.{47483,47484,47485,47486} It is fungicidal against H. capsulatum and C. posadasii with minimum fungicidal concentration (MFC) values of 170-710 and 1,420 μg/ml, respectively.{47483} Tyrosol (70-280 mg/kg) increases survival and pulmonary superoxide dismutase (SOD) activity and decreases pulmonary macrophage and neutrophil infiltration, edema, inflammation, and myeloperoxidase (MPO) activity in a mouse model of LPS-induced acute lung injury.{47484} It reduces aqueous humor TNF-α, nitric oxide (NO), and prostaglandin E2 (PGE2; Item No. 14010) levels and cellular infiltration in a rat model of ocular endotoxin-induced uveitis (EIU).{47485} Tyrosol also decreases erythrocyte aggregation, increases the oxygen transport capacity index (OTCI), and abolishes cortical microvascular rarefaction in spontaneously hypertensive rats.{47486}  

 

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SKU: 27600 - 500 g Category:

Description

A phenol with diverse biological activities; fungicidal against H. capsulatum and C. posadasii (MFCs = 170-710 and 1,420 μg/ml, respectively); increases survival and pulmonary SOD activity and decreases pulmonary macrophage and neutrophil infiltration, edema, inflammation, and MPO activity in a mouse model of LPS-induced acute lung injury

Formal name: 4-hydroxy-benzeneethanol

Synonyms:  p-HPEA|NSC 59876

Molecular weight: 138.2

CAS: 501-94-0

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Polyphenols||Research Area|Immunology & Inflammation||Research Area|Neuroscience|Ophthalmology||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Superoxide Dismutase

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