Description
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease, and drug abuse.{14414,14416,14417} TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signalling.{14444,14443,14439} The activity of TH is also regulated by phosphorylation.{14441,14440,14442} Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs.
Synonyms: TH
Immunogen: phosphopeptide corresponding to amino acid residues surrounding phospho-Ser31 of rat TH
Formulation: Peptide affinity-purified antibody
Isotype:
Applications: WB, IF (frozen sections), and IHC (frozen sections)
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunofluorescence||Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Neuroscience|Behavioral Neuroscience|Addiction Research||Research Area|Neuroscience|Behavioral Neuroscience|Depression||Research Area|Neuroscience|Behavioral Neuroscience|Schizophrenia & Psychosis||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease
