A monoamine and TAAR1 agonist (EC50s = 0.08

Tyramine – 50 g

Brand:
Cayman
CAS:
51-67-2
Storage:
-20
UN-No:
Non-Hazardous - /

Tyramine is a tyrosine-derived endogenous and dietary monoamine and trace amine-associated receptor 1 (TAAR1) agonist.{24428,22581,30099} It activates TAAR1 (EC50s = 0.08, 0.69, and 2.26 µM for rat, mouse, and human-rat chimera receptors, respectively).{24428} Tyramine also inhibits the release of norepinephrine and dopamine in isolated rat caudate nucleus (IC50s = 40.6 and 119 nM, respectively).{26354}  

 

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Description

A monoamine and TAAR1 agonist (EC50s = 0.08, 0.69, and 2.26 µM for rat, mouse, and human-rat chimera receptors, respectively); inhibits the release of norepinephrine and dopamine in isolated rat caudate nucleus (IC50s = 40.6 and 119 nM, respectively)

Formal name: 4-(2-aminoethyl)-phenol

Synonyms:  p-Tyramine|2-(4-Hydroxyphenyl)ethylamine|NSC 249188|Uteramine

Molecular weight: 137.2

CAS: 51-67-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience

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