Description
An agonist of FFA1/GPR40 (EC50 = 6.16 nM); selective for FFA1 over FFA2 (EC50 = 933 nM); reduces glucose levels in an intraperitoneal glucose tolerance test in mice; reduces glucose levels for at least 29 days with chronic oral dosing in a mouse model of diet-induced obesity
Formal name: 4-[2-[2-(cyanomethyl)phenyl]ethynyl]-2-fluoro-benzenepropanoic acid
Synonyms:
Molecular weight: 307.3
CAS: 1402601-82-4
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes