An indole; inhibits the growth of the chytrid fungal skin pathogens B. dendrobatidis and B. salamandrivorans in vitro at 100 μM; induces autostimulation and increases tryptophol production in B. dendrobatidis and B. salamandrivorans cultures as a quorum-sensing molecule at 1 μM; induces sleep in mice as assessed by loss of the righting reflex at 400 mg/kg

Tryptophol – 5 g

Brand:
Cayman
CAS:
526-55-6
Storage:
-20
UN-No:
Non-Hazardous - /

Tryptophol is an indole that has been found in plants, bacteria, fungi, and sponges and has diverse biological activities, including antifungal, sleep-promoting, and quorum-sensing-related properties.{45419,45418,45420} Tryptophol (100 μM) inhibits the growth of the chytrid fungal skin pathogens B. dendrobatidis and B. salamandrivorans in vitro.{45419} As a quorum-sensing molecule, it also induces autostimulation and increases tryptophol production in B. dendrobatidis and B. salamandrivorans cultures when used at a concentration of 1 μM. Tryptophol (400 mg/kg) induces sleep in mice as assessed by loss of the righting reflex.{45420}  

 

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SKU: 28404 - 5 g Category:

Description

An indole; inhibits the growth of the chytrid fungal skin pathogens B. dendrobatidis and B. salamandrivorans in vitro at 100 μM; induces autostimulation and increases tryptophol production in B. dendrobatidis and B. salamandrivorans cultures as a quorum-sensing molecule at 1 μM; induces sleep in mice as assessed by loss of the righting reflex at 400 mg/kg

Formal name: 1H-indole-3-ethanol

Synonyms:  IEA|NSC 3884

Molecular weight: 161.2

CAS: 526-55-6

Purity: ≥98%

Formulation: A crystalline solid

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