Description
A D2 receptor antagonist and antiemetic; prevents apomorphine-induced emesis in dogs when administered at a dose of 20 mg/kg; stimulates contraction of isolated guinea pig ileum (ED50 = 8.7 μg/mL); decreases apomorphine-induced pecking responses in pigeons by 20% and increases the latent period of pecking from 4.3 to 8 minutes when used at a dose of 20 mg/kg; enhances compensation and decreases recovery time from 70 to 32 weeks in unilaterally labyrinthectomized cats, a model of vestibular injury, when administered at a dose of 6.7 g/kg per day for 2 weeks
Formal name: N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxy-benzamide, monohydrochloride
Synonyms: Ro 2-9578
Molecular weight: 424.9
CAS: 554-92-7
Purity: ≥95%
Formulation: A solid
Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Behavioral Neuroscience