TRIM is an inhibitor of nNOS and iNOS. It exhibits IC50 values of 28.2 µM

TRIM – 500 mg

Brand:
Cayman
CAS:
25371-96-4
Storage:
-20
UN-No:
Non-Hazardous - /

TRIM is an inhibitor of nNOS and iNOS. It exhibits IC50 values of 28.2 µM, 27.0 µM, and 1.06 mM for the inhibition of nNOS (mouse), iNOS (rat), and eNOS (bovine), respectively.{5918} TRIM inhibits mouse nNOS with Ki values of 47.3 and 462 µM in the absence and presence of BH4, respectively, suggesting TRIM interferes with both arginine and tetrahydrobiopterin binding.{6635}  

 

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SKU: 81310 - 500 mg Category:

Description

TRIM is an inhibitor of nNOS and iNOS. It exhibits IC50 values of 28.2 µM, 27.0 µM, and 1.06 mM for the inhibition of nNOS (mouse), iNOS (rat), and eNOS (bovine), respectively.{5918} TRIM inhibits mouse nNOS with Ki values of 47.3 and 462 µM in the absence and presence of BH4, respectively, suggesting TRIM interferes with both arginine and tetrahydrobiopterin binding.{6635}

Formal name: 1-[2-(trifluoromethyl)phenyl]-1H-imidazole

Synonyms:  1-(α,α,α-trifluoro-o-tolyl)-Imidazole

Molecular weight: 212.2

CAS: 25371-96-4

Purity: ≥98%

Formulation: A crystalline solid

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