Description
A dihydrochalcone glucoside with diverse biological activities; reduces survival of Bel 7402 and HepG2 cancer cells at 100 μM; increases SOD and GPX activity (EC50 = 129 and 128 μM, respectively) and inhibits lipid peroxidation (IC50 = 88 μM, respectively) in rat liver homogenates; reduces hydrogen peroxide-induced cell death and production of mitochondrial ROS, prevents reduction in the mitochondrial membrane potential, and increases the activity of GPX, SOD2, and IDH2 in PC12 neuronal cells; inhibits infection by various HIV-1 strains (IC50s = 2.91-27.11 μM)
Formal name: 1-[4-(β-D-glucopyranosyloxy)-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone
Synonyms: Phloretin-4-O-glucoside
Molecular weight: 436.4
CAS: 4192-90-9
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products|Chalcones||Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Natural Products|Glycosides||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Death||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS||Research Area|Neuroscience|Neuroprotection||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Gluthathione Peroxidase||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Superoxide Dismutase
