A glycosylated derivative of trichostatin A that has been shown to induce the differentiation of a mouse erythroleukemia cell line and to increase histone H4 acetylation in B cells

Trichostatin C – 2.5 mg

Brand:
Cayman
CAS:
68676-88-0
Storage:
-20
UN-No:
Non-Hazardous - /

Trichostatin C is a glycosylated derivative of trichostatin A (Item No. 89730), the antifungal antibiotic that reversibly inhibits histone deacetylase.{4293} Trichostatin C is reported to be the first example of a glucopyranosyl hydroxamate identified in nature.{31856} It has been shown to induce the differentiation of a mouse erythroleukemia cell line and to increase histone H4 acetylation in B cells, though at higher concentrations than trichostatin A.{31857,31855}  

 

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SKU: 20220 - Category:

Description

A glycosylated derivative of trichostatin A that has been shown to induce the differentiation of a mouse erythroleukemia cell line and to increase histone H4 acetylation in B cells, though at higher concentrations than trichostatin A

Formal name: (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-(β-D-glucopyranosyloxy)-4,6-dimethyl-7-oxo-2,4-heptadienamide

Synonyms:  Antibiotic 145-A

Molecular weight: 464.5

CAS: 68676-88-0

Purity: ≥95%

Formulation: A powder

Product Type|Biochemicals||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Deacetylation

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