A synthetic corticosteroid; decreases cytokine levels

Triamcinolone acetonide – 100 mg

Brand:
Cayman
CAS:
76-25-5
Storage:
-20
UN-No:
Non-Hazardous - /

Triamcinolone acetonide is a synthetic corticosteroid.{43074} It decreases cytokine levels, the firing rate of sensory neurons, and mechanical hypersensitivity in a rat spinal nerve ligation model when used at a dose of 1.5 mg/kg prior to and following surgery for three days. Triamcinolone acetonide also decreases outflow facility in a mouse model of steroid-induced glaucoma when 20 µl of a 40 mg/ml suspension is administered subconjunctivally.{43075} Formulations containing triamcinolone acetonide are used in the treatment of diabetic macular edema.  

 

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Description

A synthetic corticosteroid; decreases cytokine levels, the firing rate of sensory neurons, and mechanical hypersensitivity in a rat spinal nerve ligation model at 1.5 mg/kg administered prior to and following surgery for three days; decreases outflow facility in a mouse model of steroid-induced glaucoma when 20 µl of a 40 mg/ml suspension is administered subconjunctivally

Formal name: 9-fluoro-11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione

Synonyms:  NSC 21916

Molecular weight: 434.5

CAS: 76-25-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Glucocorticoids & Mineralocorticoids||Research Area|Immunology & Inflammation||Research Area|Lipid Biochemistry|Sterol Lipids

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