Description
A synthetic glucocorticoid; increases expression of the calcitonin receptor in in murine osteoclast-like cells at 1 μM; reduces heat hyperalgesia and mechano-allodynia and decreases the number of TNF-α-positive mast cells in injured sciatic nerve in a rat model of chronic constriction injury-induced neuropathic pain at 3 mg/kg, s.c.; reduces levels of the glycosaminoglycans hyaluronic acid and chondroitin-4-sulfate in human keloid implants in athymic nude mice
Formal name: (11β,16α)-9-fluoro-11,16,17,21-tetrahydroxy-pregna-1,4-diene-3,20-dione
Synonyms: NSC 13397
Molecular weight: 394.4
CAS: 124-94-7
Purity: ≥98%
Formulation: A crystalline solid