Description
Thromboxane A2 (TXA2) is a potent vasoconstrictor and activator of platelet aggregation. TXA2 elicits its effects via a 7-transmembrane domain G-protein coupled receptor, the TP receptor.{6062} The TP receptor is highly expressed in platelets and is relatively less abundant in tissues such as lung, kidney, brain, spleen, thymus, monocytes, uterus, and placenta.{3167,11368,2061,4311} The apparent molecular weight for TP receptors has been reported from 37 kDa to 70 kDa, depending on different degrees of glycosylation.{8380,4311,7235} However, Cayman’s antibody consistently detects the TP receptor at 42 kDa in kidney, Hep2, and COS-7 cell samples. Cayman’s TP receptor polyclonal antibody can be used for Western blot analysis for both the TPA and TPB splice variants of the receptor on samples of human, mouse, rat, monkey and bovine origin. Use of this antibody for other species and applications has not yet been tested.
Synonyms: Prostanoid TP Receptor|Thromboxane A2 Receptor|TXA2 Receptor
Immunogen: Synthetic peptide from an internal region of mouse TP receptor
Formulation: 500 µl of Peptide affinity-purified polyclonal antibody
Isotype:
Applications: WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway
