Description
T cell immunoglobulin and mucin domain-containing molecule (TIM4) is a type I transmembrane protein from the TIM gene family that plays a vital role in regulating immune responses, including those in allergy, asthma, transplant tolerance, autoimmunity, and viral infections.{21964} TIM4 is expressed on dendritic cells and macrophages, and these proteins bind tightly to phosphatidylserine on apoptotic cells and enhance their engulfment by macrophages.{15136} It also plays an important role in the proliferation of T helper type 2 cells.{21966} TIM4 is the natural ligand of TIM1, and this binding regulates T cell proliferation.{21967} TIM4 expressing cells also regulate adaptive immunity.{21965}
Synonyms: T Cell Immunoglobulin and Mucin domain-containing protein 4|T Cell Membrane Protein 4
Immunogen: TIM4 from mouse peritoneal cells
Formulation: 400 µg of protein A-purified monoclonal antibody
Isotype:
Applications: FC and ICC
Origin:
Stability: 365 days
Application|Flow Cytometry||Application|Immunocytochemistry||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Autoimmunity||Research Area|Immunology & Inflammation|Innate Immunity|Phagocytosis||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma||Research Area|Infectious Disease|Viral Diseases
