TIM4 Monoclonal Antibody – 1 ea

Brand:
Cayman
Storage:

Immunogen: TIM4 from mouse peritoneal cells • Host: Armenian hamster • Species Reactivity: (+) Human; other species not tested • Application(s): FC and ICC  

 

Available on backorder

SKU: 10322- 1 ea Category:

Description

T cell immunoglobulin and mucin domain-containing molecule (TIM4) is a type I transmembrane protein from the TIM gene family that plays a vital role in regulating immune responses, including those in allergy, asthma, transplant tolerance, autoimmunity, and viral infections.{21964} TIM4 is expressed on dendritic cells and macrophages, and these proteins bind tightly to phosphatidylserine on apoptotic cells and enhance their engulfment by macrophages.{15136} It also plays an important role in the proliferation of T helper type 2 cells.{21966} TIM4 is the natural ligand of TIM1, and this binding regulates T cell proliferation.{21967} TIM4 expressing cells also regulate adaptive immunity.{21965}


Synonyms: T Cell Immunoglobulin and Mucin domain-containing protein 4|T Cell Membrane Protein 4

Immunogen: TIM4 from mouse peritoneal cells

Formulation: 400 µg of protein A-purified monoclonal antibody

Isotype:

Applications: FC and ICC

Origin:

Stability: 365 days


Application|Flow Cytometry||Application|Immunocytochemistry||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Autoimmunity||Research Area|Immunology & Inflammation|Innate Immunity|Phagocytosis||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma||Research Area|Infectious Disease|Viral Diseases