A pleuromutilin antibiotic; active against various mycobacteria (MICs = 0.0025-0.25 µg/ml) and various Gram-positive bacteria

Tiamulin (fumarate) – 500 mg

Brand:
Cayman
CAS:
55297-96-6
Storage:
22
UN-No:
De Minimis - 2811 / 6.1

Tiamulin is a pleuromutilin antibiotic.{33397} It is active against M. gallisepticum, M. synoviae, M. iowae, M. hyopneumoniae, M. hyosynoviae, M. hyorhinis, M. bovis, and M. agalactiae (MICs = 0.0025-0.25 µg/ml). Tiamulin is also active against various Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA).{22680} Tiamulin binds to the peptidyl transferase in the 50S ribosomal subunit to inhibit protein synthesis. Formulations containing tiamulin have been used in the treatment of veterinary enteric diseases and enzootic pneumonia.  

 

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Description

A pleuromutilin antibiotic; active against various mycobacteria (MICs = 0.0025-0.25 µg/ml) and various Gram-positive bacteria, including MRSA; binds to the peptidyl transferase in the 50S ribosomal subunit to inhibit protein synthesis

Formal name: 2-[[2-(diethylamino)ethyl]thio]-acetic acid, (3aS,4R,5S,6S,8R,9S,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester, 2E-butenedioate

Synonyms:  81723 Hfu|SQ 22,947

Molecular weight: 609.8

CAS: 55297-96-6

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia||Research Area|Infectious Disease|Bacterial Diseases|Tuberculosis

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