A natural dithiol that reversibly inhibits bacterial and yeast RNA polymerases (IC50 = 3 μg/ml); used for the analysis of mRNA stability; inhibits endothelial cell adhesion (IC50 induced angiogenesis in mice by inhibiting Hsp27 interactions with cytoskeletal elements

Thiolutin – 1 mg

Brand:
Cayman
CAS:
87-11-6
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Thiolutin is a natural dithiol that reversibly inhibits bacterial and yeast RNA polymerases (IC50 = 3 μg/ml).{20586,20588,20587} Because of this, it can be used for the analysis of mRNA stability. Thiolutin also inhibits endothelial cell adhesion (IC50 induced angiogenesis in mice by inhibiting Hsp27 interactions with cytoskeletal elements.{20584,20585}  

 

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SKU: 11350 - 1 mg Category:

Description

A natural dithiol that reversibly inhibits bacterial and yeast RNA polymerases (IC50 = 3 μg/ml); used for the analysis of mRNA stability; inhibits endothelial cell adhesion (IC50 induced angiogenesis in mice by inhibiting Hsp27 interactions with cytoskeletal elements

Formal name: N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-acetamide

Synonyms:  Acetopyrrothin|NSC 3927

Molecular weight: 228.3

CAS: 87-11-6

Purity: ≥97%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Small Molecule Inhibitors|Heat Shock Proteins||Research Area|Cancer|Angiogenesis||Research Area|Cell Biology|Cytoskeleton & Motor Proteins||Research Area|Cell Biology|ECM & Adhesion Molecules||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis

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