Description
An antibiotic originally isolated from Bacillus; has activity against Gram-positive, but not Gram-negative, bacteria; inhibits the growth of B. subtilis, B. anthracis, S. aureus, S. pyogenes, and S. pneumoniae strains in vitro (MICs = 0.2-3.13 μg/ml); exhibits antibiotic activity in a mouse model of S. pyogenes infection (ED50 = 2.91 mg/kg)
Formal name: 2′-[(11S,14Z,21S,28S)-14-ethylidene-9,10,11,12,13,14,20,21,27,28-decahydro-11,28-bis[(1R)-1-hydroxyethyl]-21-(1-hydroxy-1-methylethyl)-9,12,19,26-tetraoxo-19H,26H-8,5:18,15:25,22:32,29-tetranitrilo-5H,15H-pyrido[3,2-m][1,11,17,24,4,7,20,27]tetrathiatetraazacyclotriacontin-2-yl]-N-[(1Z)-1-[[[(2R)-2-hydroxypropyl]amino]carbonyl]-1-propen-1-yl]-[2,4′-bithiazole]-4-carboxamide
Synonyms: 44-O-Demethylthiocillin II
Molecular weight: 1,160.40
CAS: 59979-01-0
Purity: ≥95%
Formulation: A solid
Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Microtubule Dynamics||Product Type|Biochemicals|Natural Products||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia
