A broad-spectrum anthelmintic active against a variety of helminths; kills greater than 95% of adult worms from ten genera; inhibits egg production and disrupts larval development; inhibits fumarate reductase in helminths

Thiabendazole – 25 g

Brand:
Cayman
CAS:
148-79-8
Storage:
4
UN-No:
Non-Hazardous - / 9

Thiabendazole is a broad-spectrum anthelmintic that is active against a variety of helminths.{41266} In sheep, thiabendazole (50 mg/kg) kills greater than 95% of adult worms from ten genera, including Trichostrongylus, Cooperia, Nematodirus, Ostertagia, Haemonchus, Oesophagostomum, Bunostomum, Strongyloides, Chabertia, and Trichuris. It also inhibits production of eggs and disrupts larval development. Thiabendazole inhibits fumarate reductase in helminths, which inhibits succinate formation, and therefore energy production through the citric acid cycle.{41267} It also inhibits methionine aminopeptidase in E. coli (Ki = 40 nM; IC50 = 47.2 nM).{41268} Formulations containing thiabendazole have been used in the control of parasitic infections in livestock.  

 

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SKU: 23391 - 25 g Category:

Description

A broad-spectrum anthelmintic active against a variety of helminths; kills greater than 95% of adult worms from ten genera; inhibits egg production and disrupts larval development; inhibits fumarate reductase in helminths, blocking energy production through the citric acid cycle; inhibits methionine aminopeptidase in E. coli (Ki = 40 nM; IC50 = 47.2 nM)

Formal name: 2-(4-thiazolyl)-1H-benzimidazole

Synonyms:  NSC 525040|NSC 90507|TBZ|Tiabendazole

Molecular weight: 201.2

CAS: 148-79-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antiparasitics|Anthelmintics||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases

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