A flavonoid metabolite with antibacterial properties; active against MRSA-1

Terphenyllin – 1 mg

Brand:
Cayman
CAS:
52452-60-5
Storage:
-20
UN-No:
Non-Hazardous - /

Terphenyllin is a flavonoid metabolite originally isolated from A. candidus that has antibacterial and cytotoxic properties.{38478,38480} It is active against methicillin-resistant S. aureus 1 (MRSA-1), MRSA-2, and V. vulnificus (MICs = 31.27-31.47 µg/ml) and cytotoxic to HeLa, A549, and HepG2 cells (IC50s = 18.87, 12.33, and 21.2 µM, respectively).{38480} Terphenyllin inhibits HIV-1 integrase in coupled and strand transfer assays with IC50 values of 17.7 µM and 47.7 µM.{38479}  

 

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SKU: 23480 - 1 mg Category:

Description

A flavonoid metabolite with antibacterial properties; active against MRSA-1, MRSA-2, and V. vulnificus (MICs = 31.27-31.47 µg/ml); cytotoxic to HeLa, A549, and HepG2 cells (IC50s = 18.87, 12.33, and 21.2 µM, respectively); inhibits HIV-1 integrase in coupled and strand transfer assays (IC50s = 17.7 and 47.7 µM, respectively)

Formal name: 3′,6′-dimethoxy-[1,1′:4′,1”-terphenyl]-2′,4,4”-triol

Synonyms:  NSC 299114

Molecular weight: 338.4

CAS: 52452-60-5

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antivirals|Integrase Inhibitors||Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cancer|Cell Death||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS

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