An ACAT inhibitor (IC50 = 2.1 μM in rat liver microsomes); inhibits ACAT in J774 macrophages (IC50 = 0.46 μM)

Terpendole C – 500 µg

Brand:
Cayman
CAS:
156967-65-6
Storage:
-20
UN-No:
Non-Hazardous - /

Terpendole C is an indole diterpene alkaloid fungal metabolite originally isolated from A. yamanashiensis and an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 2.1 μM in rat liver microsomes).{46138} It also inhibits ACAT in J774 macrophages (IC50 = 0.46 μM) without affecting cell growth.  

 

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SKU: 26910 - 500 µg Category:

Description

An ACAT inhibitor (IC50 = 2.1 μM in rat liver microsomes); inhibits ACAT in J774 macrophages (IC50 = 0.46 μM),

Formal name: (3S,4aR,4bR,5aS,5bS,7aS,13bS,13cR,15aS,16aS)-1,4a,4b,6,7,7a,8,13,13b,13c,14,15,15a,16a-tetradecahydro-1,1,13b,13c-tetramethyl-3-(2-methyl-1-propen-1-yl)-5bH-[1,3]dioxino[5″,4″:2′,3′]oxireno[4′,4’a][1]benzopyrano[5′,6′:6,7]indeno[1,2-b]indol-5b-ol

Synonyms: 

Molecular weight: 519.7

CAS: 156967-65-6

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Alkaloids||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Cardiovascular System|Lipids & Lipoproteins|Cholesterol Metabolism

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