A synthetic chlorin with light-activated actions that accumulates in tumor cells; triggers the generation of reactive oxygen species when stimulated with light (650-652 nm) in the presence of oxygen

Temoporfin – 1 mg

Brand:
Cayman
CAS:
122341-38-2
Storage:
-20
UN-No:
Non-Hazardous - /

Temoporfin is a synthetic chlorin with light-activated actions. When administered systemically, temoporfin accumulates in tumor cells.{28585,28587} When stimulated with light (650-652 nm) in the presence of oxygen, reactive oxygen species are generated, leading to necrosis within the tumor.{28585,28587} Different approaches to using photodynamic therapy with temoporfin in palliative care are currently of interest.{28586,28588}  

 

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Description

A synthetic chlorin with light-activated actions that accumulates in tumor cells; triggers the generation of reactive oxygen species when stimulated with light (650-652 nm) in the presence of oxygen, leading to necrosis within the tumor

Formal name: 3,3′,3”,3”’-(7,8-dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-phenol

Synonyms:  m-THPC|Foscan|KW 2345

Molecular weight: 680.8

CAS: 122341-38-2

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Research Area|Cancer|Cell Death|Necrosis||Research Area|Cancer|Tumor Microenvironment||Research Area|Oxidative Stress & Reactive Species|Pro-oxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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