A precursor in the synthesis of PROTACs; has also been used as an intermediate in the synthesis of HDAC6 and ALK degraders

TC-E3 5032 – 100 mg

Brand:
Cayman
CAS:
835616-60-9
Storage:
-20
UN-No:
Non-Hazardous - /

TC-E3 5032 is a precursor in the synthesis of homodimeric proteolysis-targeting chimera technologies (PROTACs).{46128} It has been used to attach various linkers at position 4 to produce alkylated pomalidomide derivatives as intermediates in the synthesis of homodimeric PROTACs. It has also been used as an intermediate in the synthesis of HDAC6 and anaplastic lymphoma kinase (ALK) degraders.{46129,46130}  

 

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SKU: 26147 - 100 mg Category:

Description

A precursor in the synthesis of PROTACs; has also been used as an intermediate in the synthesis of HDAC6 and ALK degraders

Formal name: 2-(2,6-dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione

Synonyms: 

Molecular weight: 276.2

CAS: 835616-60-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|PROTACs||Product Type|Biochemicals|Synthetic Intermediates & Building Blocks||Research Area|Cell Biology|Proteolysis|Ubiquitin/Proteasome System||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Deacetylation

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