A synthetic taurine analog with broad bactericidal and fungicidal activity; binds to the extracellular wall of bacteria

Taurolidine – 50 mg

Brand:
Cayman
CAS:
19388-87-5
Storage:
-20
UN-No:
Non-Hazardous - /

Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.{25038} Taurolidine and its metabolites mimic mannose by binding to the extracellular wall of bacteria, blocking adherence to epithelial and fibroblast cells.{25039} In addition to modulating immunoregulatory systems, taurolidine induces autophagy, apoptosis, and necrosis in human cancer cells.{25038,25042,25041,25040} It produces cell death in malignant mesothelioma cells by oxidative stress in concert with inhibition of Akt signaling.{25043}  

 

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Description

A synthetic taurine analog with broad bactericidal and fungicidal activity; binds to the extracellular wall of bacteria, blocking adherence to epithelial and fibroblast cells; induces autophagy, apoptosis, and necrosis in human cancer cells

Formal name: 4,4′-methylenebis(tetrahydro-1,2H,4-thiadiazine) 1,1,1′,1′-tetraoxide

Synonyms: 

Molecular weight: 284.4

CAS: 19388-87-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Research Area|Cancer|Autophagy||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Death|Necrosis||Research Area|Cancer|Cell Signaling|PI3K/Akt/mTOR Signaling||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Cell Death|Necrosis||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking|Autophagy||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Fungal Diseases

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