A taurine-conjugated form of deoxycholic acid stimulates chloride ion secretion through calcium-activated chloride ion channels and CFTR in Calu-3 airway epithelial cell monolayers when applied basolaterally; serum levels increase approximately 5-fold within two hours during an oral lipid tolerance test in humans

Taurodeoxycholic Acid (sodium salt) – 5 g

Brand:
Cayman
CAS:
1180-95-6
Storage:
-20
UN-No:
Non-Hazardous - /

Taurodeoxycholic acid is a taurine-conjugated form of the secondary bile acid deoxycholic acid (Item No. 20756 | 18231).{33902} Taurodeoxycholic acid stimulates chloride ion secretion through calcium-activated chloride ion channels and cystic fibrosis transmembrane conductance regulator (CFTR) in Calu-3 airway epithelial cell monolayers when applied basolaterally.{29486} Serum levels of taurodeoxycholic acid increase approximately 5-fold within two hours during an oral lipid tolerance test in humans.{33902}  

 

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Description

A taurine-conjugated form of deoxycholic acid stimulates chloride ion secretion through calcium-activated chloride ion channels and CFTR in Calu-3 airway epithelial cell monolayers when applied basolaterally; serum levels increase approximately 5-fold within two hours during an oral lipid tolerance test in humans

Formal name: 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid, monosodium salt

Synonyms:  Sodium taurodeoxycholate|TDCA​

Molecular weight: 521.7

CAS: 1180-95-6

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Endocrinology & Metabolism|Bile Acids & Microbiome

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