A sym-triazine with diverse biological activities; inhibits in vitro Aβ42 fibrilization at 20 µM; inhibits AChE (IC50 = 0.465 µM for the human erythrocyte enzyme); increases neuronal cellular process length and branching and synaptophysin protein levels in differentiated human SH-SY5Y neuronal cells

TAE-1 – 1 mg

Brand:
Cayman
CAS:
1414469-59-2
Storage:
-20
UN-No:
Non-Hazardous - /

TAE-1 is a sym-triazine with diverse biological activities.{53142} It inhibits in vitro amyloid-β (1-42) (Aβ42; Item No. 20574) fibrilization when used at a concentration of 20 µM. TAE-1 inhibits acetylcholinesterase (AChE; IC50 = 0.465 µM for the human erythrocyte enzyme). It also increases neuronal cellular process length and branching and synaptophysin protein levels in differentiated human SH-SY5Y neuronal cells.  

 

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Description

A sym-triazine with diverse biological activities; inhibits in vitro Aβ42 fibrilization at 20 µM; inhibits AChE (IC50 = 0.465 µM for the human erythrocyte enzyme); increases neuronal cellular process length and branching and synaptophysin protein levels in differentiated human SH-SY5Y neuronal cells

Formal name: 2,2′,2′-[1,3,5-triazine-2,4,6-triyltris(oxy-4,1-phenylenecarbonyloxy)]tris[N,N,N-trimethyl-ethanaminium, triiodide

Synonyms: 

Molecular weight: 1,128.60

CAS: 1414469-59-2

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Acetylcholine Turnover||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease

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