An indole alkaloid; inhibits Aβ42 fibril formation and disintegrates preformed Aβ42 fibrils in vitro at 10 μM; an intermediate in the biosynthesis of vindoline

Tabersonine – 10 mg

Brand:
Cayman
CAS:
4429-63-4
Storage:
-20
UN-No:
Non-Hazardous - /

Tabersonine is an indole alkaloid that has been found in the beans of Voacanga.{43901} It inhibits amyloid-β (1-42) (Aβ42) fibril formation and disintegrates preformed Aβ42 fibrils in vitro when used at a concentration of 10 μM. Tabersonine is an intermediate in the biosynthesis of vindoline, a precursor in the synthesis of anticancer agents.{43907}  

 

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SKU: 26848 - 10 mg Category:

Description

An indole alkaloid; inhibits Aβ42 fibril formation and disintegrates preformed Aβ42 fibrils in vitro at 10 μM; an intermediate in the biosynthesis of vindoline

Formal name: (5α,12R,19α)-2,3,6,7-tetradehydro-aspidospermidine-3-carboxylic acid, methyl ester

Synonyms:  (–)-Tabersonine

Molecular weight: 336.4

CAS: 4429-63-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Alkaloids||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease

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