T-26c – 5 mg

Brand:
Cayman
CAS:
869296-13-9
Storage:
-20
UN-No:
Non-Hazardous - /

T-26c is a selective inhibitor of matrix metalloproteinase-13 (MMP-13; IC50 = 0.0069 nM).{42897} It is selective for MMP-13 over MMP-1, -2, -3, -7, -8, -9, -10, and -14 (IC50s = ≥18 nM). T-26c inhibits IL-1β- and oncostatin M-induced collagen degradation in bovine nasal septum cartilage explants by 87.4% when used at a concentration of 0.1 μM.  

 

Available on backorder

SKU: 19962 - Category:

Description

A selective inhibitor of MMP-13 (IC50 = 0.0069 nM); selective for MMP-13 over MMP-1, -2, -3, -7, -8, -9, -10, and -14 (IC50s = ≥18 nM); inhibits IL-1β- and oncostatin M-induced collagen degradation in bovine nasal septum cartilage explants by 87.4% at 0.1 μM


Formal name: 4-[[[1,4-dihydro-2-[[[(3-methoxyphenyl)methyl]amino]carbonyl]-4-oxothieno[2,3-d]pyrimidin-5-yl]methoxy]methyl]-benzoic acid

Synonyms: 

Molecular weight: 479.5

CAS: 869296-13-9

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling