Sulprostone is a metabolism resistant synthetic analog of PGE2.{1993} It is a selective agonist for EP3 receptors with a Ki value of 0.35 nM at the human recombinant EP3-III receptor and an IC50 of 0.01 µM for the inhibition of PGE2 binding.{8322

Sulprostone – 500 µg

Brand:
Cayman
CAS:
60325-46-4
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Sulprostone is a metabolism resistant synthetic analog of PGE2.{1993} It is a selective agonist for EP3 receptors with a Ki value of 0.35 nM at the human recombinant EP3-III receptor and an IC50 of 0.01 µM for the inhibition of PGE2 binding.{8322,3390} Sulprostone is a potent stimulator of uterine smooth muscle contractions with high abortifacient activity.{3335,2462}  

 

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Description

Sulprostone is a metabolism resistant synthetic analog of PGE2.{1993} It is a selective agonist for EP3 receptors with a Ki value of 0.35 nM at the human recombinant EP3-III receptor and an IC50 of 0.01 µM for the inhibition of PGE2 binding.{8322,3390} Sulprostone is a potent stimulator of uterine smooth muscle contractions with high abortifacient activity.{3335,2462}

Formal name: N-(methylsulfonyl)-9-oxo-11α,15R-dihydroxy-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-amide

Synonyms: 

Molecular weight: 465.6

CAS: 60325-46-4

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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