A penicillanic acid sulfone that acts as an irreversible inhibitor of β-lactamases; effective against a wide variety of serine β-lactamases produced by common Gram-negative and Gram-positive aerobes and anaerobes

Sulbactam – 5 g

Brand:
Cayman
CAS:
68373-14-8
Storage:
-20
UN-No:
Non-Hazardous - /

β-Lactams are a large class of antibiotics that includes penicillins, cephalosporins, carbapenems, and monobactams.{25960} Resistance against β-lactam antibiotics can result from the production of β-lactamases, which is a common mechanism employed by Gram-negative bacteria.{25960,27765} Sulbactam is a penicillanic acid sulfone that acts as an irreversible inhibitor of β-lactamases.{27903} It is effective against a wide variety of serine β-lactamases produced by common Gram-negative and Gram-positive aerobes and anaerobes.{27902,27900,27901} However, it is not effective against metallo-β-lactamases, cephalosporinases, or oxacillinases.{27901}  

 

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Description

A penicillanic acid sulfone that acts as an irreversible inhibitor of β-lactamases; effective against a wide variety of serine β-lactamases produced by common Gram-negative and Gram-positive aerobes and anaerobes

Formal name: (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 4,4-dioxide

Synonyms:  CP 45,899|Penicillanic Acid Dioxide

Molecular weight: 233.2

CAS: 68373-14-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Small Molecule Inhibitors

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