A steroid-based neuromuscular blocker reversing agent; selectively reverses rocuronium-induced neuromuscular blockade over that induced by mivacurium or atracurium in anesthetized rhesus monkeys; prevents formation of postoperative peritoneal adhesions in rats; increases the total number of neurons in the hippocampus compared to control and improves motor coordination in a beam walking test in a rat model of ischemia-reperfusion injury (16 and 100 mg/kg)

Sugammadex (sodium salt) – 5 mg

Brand:
Cayman
CAS:
343306-79-6
Storage:
-20
UN-No:
Non-Hazardous - /

Sugammadex is a synthetic derivative of γ-cyclodextrin and a steroid-based neuromuscular blocker reversing agent.{40796} It binds rocuronium (Item No. 23698) within its cyclodextrin ring and selectively reverses rocuronium-induced neuromuscular blockade over that induced by mivacurium (Item No. 23610) or atracurium (Item No. 17796) in anesthetized rhesus monkeys. Sugammadex also prevents formation of postoperative peritoneal adhesions in rats.{40797} In a rat model of ischemia-reperfusion injury, sugammadex (16 and 100 mg/kg) increases the total number of neurons in the hippocampus compared to control and improves motor coordination in a beam walking test.{40798}  

 

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SKU: 24096 - 5 mg Category:

Description

A steroid-based neuromuscular blocker reversing agent; selectively reverses rocuronium-induced neuromuscular blockade over that induced by mivacurium or atracurium in anesthetized rhesus monkeys; prevents formation of postoperative peritoneal adhesions in rats; increases the total number of neurons in the hippocampus compared to control and improves motor coordination in a beam walking test in a rat model of ischemia-reperfusion injury (16 and 100 mg/kg)

Formal name: 6A,6B,6C,6D,6E,6F,6G,6H-octakis-S-(2-carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-γ-cyclodextrin, octosodium salt

Synonyms:  ORG 25969

Molecular weight: 2,178.00

CAS: 343306-79-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cardiovascular System|Cardiovascular Diseases|Stroke||Research Area|Neuroscience|Behavioral Neuroscience

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