A basic aluminum sucrose sulfate complex with gastroprotective activity; inhibits rat pepsin and inhibits pepsin activity in isolated human gastric juice; inhibits pyloric ligation-

Sucralfate – 500 mg

Brand:
Cayman
CAS:
54182-58-0
Storage:
-20
UN-No:
Non-Hazardous - /

Sucralfate is a basic aluminum sucrose sulfate complex that has gastroprotective activity.{46263} It inhibits rat pepsin in a concentration-dependent manner and pepsin activity in isolated human gastric juice. It also inhibits ulcer formation induced by pyloric ligation, indomethacin (Item No. 70270), or cysteamine (Item No. 22193) in rats. Sucralfate (5,600 mg/animal) is protective against neutral ethanol and acidified taurocholic acid-induced damage in a rat model of hydrochloric acid-induced gastric mucosal damage, increasing the pH and reducing the disappearance of hydrogen ions.{46264} Formulations containing sucralfate have been used as antacids in the treatment of duodenal ulcer.  

 

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SKU: 27882 - 500 mg Category:

Description

A basic aluminum sucrose sulfate complex with gastroprotective activity; inhibits rat pepsin and inhibits pepsin activity in isolated human gastric juice; inhibits pyloric ligation-, indomethacin-, and cysteamine-induced ulcer formation in rats; protective against neutral ethanol and acidified taurocholic acid-induced damage in a rat model of hydrochloric acid-induced gastric mucosal damage at 5,600 mg/animal

Formal name: hexadeca-μ-hydroxytetracosahydroxy[μ8-[[1,3,4,6-tetra-O-sulfo-β-D-fructofuranosyl α-D-glucopyranoside tetrakis(sulfato-κO’)](8-)]]hexadeca-aluminum

Synonyms: 

Molecular weight: 2,086.70

CAS: 54182-58-0

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals||Research Area|Endocrinology & Metabolism|Bile Acids & Microbiome||Research Area|Immunology & Inflammation|Gastric Disease|Peptic Ulcers

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