A chromogenic substrate that can be cleaved by cathepsin G (Km = 1.7 mM)

Suc-AAPF-pNA – 25 mg

Brand:
Cayman
CAS:
70967-97-4
Storage:
-20
UN-No:
Non-Hazardous - /

Suc-AAPF-pNA is a chromogenic substrate that can be cleaved by cathepsin G (Km = 1.7 mM), subtilisins, chymotrypsin (Km = 60 µM), chymase (Km = 4 mM), and cyclophilin, but not neutrophil elastase.{23997,23999,21214,23998} Release of p-nitroanilide is monitored at 405-410 nm. This substrate can be used for inhibitor screening and kinetic analysis.  

 

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Description

A chromogenic substrate that can be cleaved by cathepsin G (Km = 1.7 mM), subtilisins, chymotrypsin (Km = 60 µM), chymase (Km = 4 mM), and cyclophilin; used for inhibitor screening and kinetic analysis

Formal name: N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-phenylalaninamide

Synonyms:  Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide

Molecular weight: 624.7

CAS: 70967-97-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Research Area

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