An inhibitor of the tyrosine kinase domains of VEGFR2

SU 5402 – 5 mg

Brand:
Cayman
CAS:
215543-92-3
Storage:
-20
UN-No:
Non-Hazardous - /

SU 5402 is an inhibitor of the tyrosine kinase domains of VEGFR2, FGFR1, and PDGFRβ (IC50s = 0.02, 0.03, and 0.51 µM, respectively).{32055} It is much less effective against other receptor tyrosine kinases.{32055} SU 5402 is commonly used to evaluate the role of FGFR1 in cellular functions.{17827,16878,32053,32054}  

 

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Description

An inhibitor of the tyrosine kinase domains of VEGFR2, FGFR1, and PDGFRβ (IC50s = 0.02, 0.03, and 0.51 µM, respectively)

Formal name: 2-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid

Synonyms: 

Molecular weight: 296.3

CAS: 215543-92-3

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|FGFR Family||Product Type|Biochemicals|Kinase Inhibitors|PDGFR Family||Product Type|Biochemicals|Kinase Inhibitors|VEGFR Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling|Growth Factor Receptors

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