Cayman’s STAT-8-isoprostane ELISA is a competitive assay that permits the rapid measurement of 8-iso PGF2α from biological samples

STAT-8-Isoprostane ELISA Kit – 480 strip wells

Brand:
Cayman
Storage:
-20

The isoprostanes are a family of eicosanoids of non-enzymatic origin produced by the random oxidation of tissue phospholipids by oxygen radicals. At least one of the isoprostanes, 8-isoprostane (8-iso PGF2α), has biological activity and has implicated as a causative mediator and specific marker of free radical-induced damage in a variety of diseases related to oxidative stress.{1053,1381,9138,9117} Cayman Chemical’s STAT-8-isoprostane ELISA is a competitive assay that permits the rapid measurement of 8-iso PGF2α from biological samples, requiring only 1 hour incubation and development times for each step. This assay format is the similar to that employed in Cayman’s popular 8-isoprostane ELISA (Item No. 516351) with the only change being the use of an alkaline phosphatase tracer in place of an AChE tracer. While Item No. 516351 offers superior sensitivity (IC50 ~35 pg/ml), the new STAT-8-isoprostane Assay offers the convenience of a fast assay while still achieving an IC50 of 180 pg/ml and a detection limit (80% B/B0) of approximately 45 pg/ml.  

 

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SKU: 500431 - 480 strip wells Category:

Description

Cayman’s STAT-8-isoprostane ELISA is a competitive assay that permits the rapid measurement of 8-iso PGF2α from biological samples, requiring only 1 hour incubation and development times for each step. This assay format is similar to that employed in Cayman’s original 8-isoprostane ELISA (Item No. 516351) with the only change being the use of an alkaline phosphatase tracer in place of an AChE tracer. While Item No. 516351 offers superior sensitivity (IC50 = ~35 pg/ml), the STAT-8-isoprostane assay offers the convenience of a fast assay while still achieving an IC50 value of 180 pg/ml and a detection limit (80% B/B0) of approximately 45 pg/ml.

Formulation:

Formal name:

Synonyms:  iPF2α-III Alkaline Phosphatase|STAT-8-epi Prostaglandin F2α|STAT-8-iso Prostaglandin F2α|STAT-8-Isoprostane EIA Kit

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Imunogen:

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Clone:

Purity:

Origin: Animal/Mouse|Animal/Bovine|Animal/Rabbit

Application|ELISA||Product Type|Assay Kits|ELISA||Research Area|Lipid Biochemistry|Reactive O2/N2 Pathways||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation

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