Src Kinase Inhibitor I – 10 mg

Brand:
Cayman
CAS:
179248-59-0
Storage:
-20
UN-No:
De Minimis - 3077 / 9

The Src kinases constitute a family of non-receptor tyrosine kinases, which includes Src and Lck. Src kinase inhibitor I is a potent competitive inhibitor of both Src and Lck (IC50 = 44 and 88 nM, respectively), as well as Csk and Yes.{23054,17331} It less effectively blocks the receptor tyrosine kinases VEGFR2 and C-fms (IC50 = 0.32 and 30 µM), as well as a long list of serine/threonine kinases.{23054,17331} Src Kinase Inhibitor I also inhibits receptor-interacting protein-2 with an IC50 value of 26 nM.{17331}  

 

SKU: - Category:

Description

A potent competitive inhibitor of both Src and Lck (IC50 = 44 and 88 nM, respectively), as well as Csk and Yes; also inhibits RIP-2


Formal name: 6,7-dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine

Synonyms: 

Molecular weight: 373.4

CAS: 179248-59-0

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Kinase Inhibitors|SRC Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling