SR 4370 – 5 mg

Brand:
Cayman
CAS:
1816294-67-3
Storage:
-20
UN-No:
Non-Hazardous - /

SR 4370 is an inhibitor of histone deacetylase 3 (HDAC3; IC50 = 6 nM).{47684} It is selective for HDAC3 over HDAC1, -2, -6, and -8 (IC50s = 0.13, 0.58, 3.7, and 2.3 µM, respectively). SR 4370 decreases viability of MDA-MB-231 human breast cancer cells with an IC50 value of 12.6 µM.  

 

Available on backorder

SKU: 25543 - 5 mg Category:

Description

An HDAC3 inhibitor (IC50 = 6 nM); selective for HDAC3 over HDAC1, -2, -6, and -8 (IC50s = 0.13, 0.58, 3.7 and 2.3 µM, respectively); decreases viability of MDA-MB-231 cancer cells (IC50 = 12.6 µM)


Formal name: 2′,3′-difluoro-[1,1′-biphenyl]-4-carboxylic acid, 2-butylhydrazide

Synonyms: 

Molecular weight: 304.3

CAS: 1816294-67-3

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Small Molecule Inhibitors|Deacetylases||Research Area