A JNK3 inhibitor (IC50 = 7 nM); selective for JNK3 over JNK1 and p38 MAP kinase (IC50s = 0.17 and >20 µM

SR 3576 – 5 mg

Brand:
Cayman
CAS:
1164153-22-3
Storage:
-20
UN-No:
Non-Hazardous - /

SR 3576 is a JNK3 inhibitor (IC50 = 7 nM).{57073} It is selective for JNK3 over JNK1 and p38 MAP kinase (IC50s = 0.17 and >20 µM, respectively). It inhibits c-Jun phosphorylation in INS-1 cells (IC50 = 1.3 µM).  

 

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SKU: 20215 - Category:

Description

A JNK3 inhibitor (IC50 = 7 nM); selective for JNK3 over JNK1 and p38 MAP kinase (IC50s = 0.17 and >20 µM, respectively); inhibits c-Jun phosphorylation in INS-1 cells (IC50 = 1.3 µM)

Formal name: 3-[4-[[[(3-methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide

Synonyms: 

Molecular weight: 501.5

CAS: 1164153-22-3

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Kinase Inhibitors|JNK||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors

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