Description
An inverse agonist of PPARγ (IC50 = 30 nM) that represses both transactivation in a promoter:reporter assay and expression of FABP4 in differentiating murine preadipocytes; promotes osteogenesis in cultured human MSCs
Formal name: 4′-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-[1,1′-biphenyl]-2-carboxylic acid
Synonyms:
Molecular weight: 558.7
CAS: 1415252-61-7
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Receptor Pharmacology|Inverse Agonists||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling||Research Area|Endocrinology & Metabolism|Hormones & Receptors|PPARs