A fluorescent chloride indicator; has been used to assess voltage-sensitive chloride transport in placental microvillus vesicles; has been used to continuously quantify PTH-

SPQ – 500 mg

Brand:
Cayman
CAS:
83907-40-8
Storage:
-20
UN-No:
Non-Hazardous - /

SPQ is a fluorescent chloride indicator.{43896} Its fluorescence is rapidly quenched by chloride in vitro. It has been used to assess voltage-sensitive chloride transport in placental microvillus vesicles. It has also been used to continuously quantify intracellular calcium efflux induced by parathyroid hormone, forskolin (Item No. 11018), and phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in isolated human erythrocytes.{43897} In addition, SPQ has been used to determine the type of ion conductance induced by the cystic fibrosis transmembrane conductance regulator (CFTR) in HEK293 cells expressing pTrial10-CRTR2.{43898} SPQ displays excitation maxima of 320 and 350 nm and an emission maximum of 445 nm.{43896}  

 

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SKU: 27604 - 500 mg Category:

Description

A fluorescent chloride indicator; has been used to assess voltage-sensitive chloride transport in placental microvillus vesicles; has been used to continuously quantify PTH-, forskolin-, and PMA-induced intracellular calcium efflux in isolated human erythrocytes; has been used to determine the type of ion conductance induced by CFTR in HEK293 cells expressing pTrial10-CRTR2; ex/em = 320 and 350/445 nm, respectively

Formal name: 6-methoxy-1-(3-sulfopropyl)-quinolinium, inner salt

Synonyms: 

Molecular weight: 281.3

CAS: 83907-40-8

Purity: ≥95%

Formulation: A solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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