Spiromesifen – 50 mg

Brand:
Cayman
CAS:
283594-90-1
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Spiromesifen is an insecticide and acaricide that reduces lipid biosynthesis via inhibition of acetyl-CoA carboxylase.{43346,43347} It inhibits chitinase from Egyptian cotton leafworm (S. littoralis) larvae (IC50s = 0.60 and 0.72 μM for enzyme isolated from lab and field strains, respectively).{43348} It induces toxicity in whitefly (T. vaporariorum) nymphs (LC50 = 0.61 mg/L), spider mite (T. cinnabarinus) eggs (LC50 = 0.16 mg/kg), and second instar larvae of S. littoralis lab and field strains (LC50s = 0.44 and 0.68 ppm, respectively, at 72 hours post-application).{43346,43347,43348} Spiromesifen (600 mg/kg) also induces 50, 60, and 70% mortality in the Lepidoptera pests H. armigera, O. nubilalis, and P. xylostella, respectively, and induces 100% mortality in M. separata when used at a dose of 100 mg/kg.{43347} It induces toxicity in D. magna (EC50 = >0.092 mg a.s./L) and the fish species O. mykiss and L. macrochirus (LC50s = 0.016 and >0.034 mg a.s./L, respectively) but not rats (LD50 = >2,000 mg/kg).{43350} Spiromesifen also inhibits the human GST isozyme GSTA1-1 (IC50 = 12.1 μM).{43349}  

 

Available on backorder

SKU: 25822 - 50 mg Category:

Description

An insecticide and acaricide; reduces lipid biosynthesis; inhibits acetyl-CoA carboxylase; inhibits chitinase from S. littoralis larvae (IC50s = 0.60 and 0.72 μM for enzyme isolated from lab and field strains, respectively); induces toxicity in whitefly nymphs (LC50 = 0.61 mg/L), spider mite eggs (LC50 = 0.16 mg/kg), and second instar larvae of S. littoralis lab and field strains (LC50s = 0.44 and 0.68 ppm, respectively, at 72 hours post-application); induces 50, 60, and 70% mortality in H. armigera, O. nubilalis, and P. xylostella, respectively, at 600 mg/kg; induces 100% mortality in M. separata at 100 mg/kg; induces toxicity in D. magna (EC50 = >0.092 mg a.s./L) and O. mykiss and L. macrochirus (LC50s = 0.016 and >0.034 mg a.s./L, respectively) but not rats (LD50 = >2,000 mg/kg); inhibits the human GST isozyme GSTA1-1 (IC50 = 12.1 μM)


Formal name: 3,3-dimethyl-butanoic acid, 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl ester

Synonyms: 

Molecular weight: 370.5

CAS: 283594-90-1

Purity: ≥95%

Formulation: A solid


Product Type|Biochemicals|Pesticides|Acaricides||Product Type|Biochemicals|Pesticides|Insecticides||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Toxicology|Environmental|Agriculture||Research Area|Toxicology|Environmental|Aquatic Systems