Description
SPHK 1 catalyzes the phosphorylation of sphingosine to sphingosine-1-phosphate. This reaction plays an important role in determining cell proliferation versus cell death.{13916,5545} SPHK 1 is found in a wide variety of tissues and cell types including kidney, liver, spleen, heart, platelets, and human tumors. On a cellular level, it is found in the cytosolic and membrane fractions.{14482} Based on the amino acid sequence, this protein has a molecular weight of approximately 43 kDa. The observed band at 50 kDa may be explained by some reported post translational modifications.{14483}
Synonyms: SK 1|SPHK 1|SPK 1
Immunogen: Synthetic peptide from an internal region of human SPHK 1
Formulation: Lyophilized peptide affinity-purified antibody
Isotype:
Applications: ICC and WB; other applications not tested
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunocytochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Lipid Biochemistry|Sphingolipids
