Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine inhibits PKC and phosphatidic acid phosphohydrolase

Sphingosine (d18:1) – 10 mg

Brand:
Cayman
CAS:
123-78-4
Storage:
-20
UN-No:
Non-Hazardous - /

Sphingosine (d18:1) is formed primarily from the breakdown of ceramide.{13592} Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.{13592} Phosphorylation of sphingosine by sphingosine kinases 1 and 2 (SPHK 1, SPHK 2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.{11895,12477,10628}  

 

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SKU: 10007907 - 10 mg Category:

Description

Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine inhibits PKC and phosphatidic acid phosphohydrolase, whereas it activates PLD and DAG kinase. Phosphorylation of sphingosine by SPHK 1 and SPHK 2 produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.

Formal name: 2S-amino-4E-octadecene-1,3R-diol

Synonyms:  (−)-Sphingosine|D-erythro-Sphingosine C-18

Molecular weight: 299.5

CAS: 123-78-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|PKC||Product Type|Biochemicals|Lipids|Sphingolipids||Product Type|Biochemicals|Small Molecule Activators|Kinases||Product Type|Biochemicals|Small Molecule Activators|Lipases||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Product Type|Biochemicals|Small Molecule Inhibitors|Phosphatases||Research Area|Cell Biology|Cell Signaling||Research Area|Lipid Biochemistry|Sphingolipids

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