A bioactive sphingolipid; has been found in B. mori

Sphingosine (d14:1) – 1 mg

Brand:
Cayman
CAS:
24558-60-9
Storage:
-20
UN-No:
Non-Hazardous - /

Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. mori (silkworm), P. clarkii (crayfish), and A. aurita (jellyfish) extracts.{38741,38742,38743} It increases the germination rate of N. rileyi, an entomopathogenic fungus, with an EC50 value of 10.2 nM.{38741} Sphingosine (d14:1) inhibits protein kinase C (PKC) in vitro (IC50 = 7.3 mol%) as well as superoxide generation induced by phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in neutrophils and reduces growth of CHO cells (IC50s = 19 and 8 μM, respectively).{15200} [Matreya, LLC. Catalog No. 1833]  

 

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SKU: 24373 - 1 mg Category:

Description

A bioactive sphingolipid; has been found in B. mori, P. clarkii, and A. aurita extracts; increases the germination rate of N. rileyi (EC50 = 10.2 nM); inhibits PKC in vitro (IC50 = 7.3 mol %); inhibits PMA-induced superoxide generation in neutrophils and reduces growth of CHO cells (IC50s = 19 and 8 μM, respectively),

Formal name: 2S-amino-4E-tetradecene-1,3R-diol

Synonyms:  D-erythro-Sphingosine C14

Molecular weight: 243.4

CAS: 24558-60-9

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Kinase Inhibitors|PKC||Product Type|Biochemicals|Lipids|Sphingolipids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Sphingolipids

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