A steroidal glycoalkaloid with diverse biological activities; inhibits the growth of HT-29 and HepG2 cells by 68.4 and 79.3%

Solasonine – 10 mg

Brand:
Cayman
CAS:
19121-58-5
Storage:
-20
UN-No:
Non-Hazardous - /

Solasonine is a steroidal glycoalkaloid that has been found in S. melongena and has diverse biological activities, including anticancer, antiviral, and antiparasitic properties.{61002,61003,61004} It inhibits the growth of HT-29 and HepG2 cells by 68.4 and 79.3%, respectively, when used at a concentration of 10 μg/ml.{61002} Solasonine inhibits expression of hepatitis B virus surface antigen (HBsAg) in HepG2 2.2.15 cells (IC50 = 5.9 μM).{61003} It decreases survival of blood stream forms and epimastigotes of two T. cruzi strains in a concentration-dependent manner.{61004}  

 

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SKU: 28111 - 10 mg Category:

Description

A steroidal glycoalkaloid with diverse biological activities; inhibits the growth of HT-29 and HepG2 cells by 68.4 and 79.3%, respectively, at 10 μg/ml; inhibits expression of HBsAg in HepG2 2.2.15 cells (IC50 = 5.9 μM); decreases survival of blood stream forms and epimastigotes of two T. cruzi strains in a concentration-dependent manner

Formal name: (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-galactopyranoside

Synonyms:  NSC 82149|α-Solasonine

Molecular weight: 884.1

CAS: 19121-58-5

Purity: ≥98%

Formulation: A crystalline solid

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