An alkaloid with diverse biological activities; reduces glutamate-induced excitotoxicity in PC12 cells at 40 µM; inhibits cell invasion and migration of

Solasodine – 10 mg

Brand:
Cayman
CAS:
126-17-0
Storage:
-20
UN-No:
Non-Hazardous - /

Solasodine is an alkaloid that has been found in Solanum and has diverse biological activities.{57259,57261,57260} It reduces glutamate-induced excitotoxicity in PC12 cells when used at a concentration of 40 µM.{57259} Solasodine (40 µM) inhibits cell invasion and migration of, as well as reverses TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in, HCT116 cells.{57261} Solasodine (30 and 50 mg/kg) reduces tumor growth and inhibits EMT in an HCT116 mouse xenograft model. It also reduces paw edema induced by carrageenan or arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) in rats when administered at a dose of 75 mg/kg.{57260}  

 

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SKU: 28112 - 10 mg Category:

Description

An alkaloid with diverse biological activities; reduces glutamate-induced excitotoxicity in PC12 cells at 40 µM; inhibits cell invasion and migration of, as well as reverses TGF-β1-induced EMT in, HCT116 cells at 40 µM; reduces tumor growth and inhibits EMT in an HCT116 mouse xenograft model at 30 and 50 mg/kg; reduces carrageenan or arachidonic acid-induced paw edema at 75 mg/kg

Formal name: (3β,22α,25R)-spirosol-5-en-3-ol

Synonyms:  (−)-Solasodine|NSC 178260|NSC 179187|Purapuridine|Solancarpidine|Solasod-5-en-3β-ol

Molecular weight: 413.6

CAS: 126-17-0

Purity: ≥98%

Formulation: A crystalline solid

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