A derivative of pyruvate that inhibits the conversion of pyruvate to lactate via lactate dehydrogenase

Sodium Oxamate – 25 g

Brand:
Cayman
CAS:
565-73-1
Storage:
22
UN-No:
Non-Hazardous - /

Sodium oxamate is a derivative of pyruvate that inhibits the conversion of pyruvate to lactate via lactate dehydrogenase, thus disrupting glycolysis.{30659} Because cancer cells produce a large amount of energy via aerobic glycolysis, sodium oxamate has been studied as an inhibitor of carbohydrate metabolism in various tumors.{30660,30662,30658,30661}  

 

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Description

A derivative of pyruvate that inhibits the conversion of pyruvate to lactate via lactate dehydrogenase, thus disrupting glycolysis; studied as an inhibitor of glycolysis in various tumors

Formal name: 2-amino-2-oxo-acetic acid, monosodium salt

Synonyms:  Oxalic Acid monoamide|Oxamic Acid

Molecular weight: 111

CAS: 565-73-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cancer|Metabolism||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism

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